More regions, smarter filters, always up to date: Karthus probuilds reimagined. See how the best Karthus pro builds Karthus.
For each champ, we prioritize pros by: popularity, performance, and regional skill.
Who To Trust: Each region’s pros build Karthus differently. Use these Karthus runes and Mythic items to select the best Karthus probuild for you.
Pro Karthus Items By Popularity
Best Karthus Regions (Solo Q Win Rate)